The structure of human CD23 and its interactions with IgE and CD21

The low-affinity immunoglobulin E (IgE) receptor, CD23 (FcɛRII), binds both IgE and CD21 and, through these interactions, regulates the synthesis of IgE, the antibody isotype that mediates the allergic response. We have determined the three-dimensional structure of the C-type lectin domain of CD23 i...

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Autors principals: Hibbert, Richard G., Teriete, Peter, Grundy, Gabrielle J., Beavil, Rebecca L., Reljić, Rajko, Holers, V. Michael, Hannan, Jonathan P., Sutton, Brian J., Gould, Hannah J., McDonnell, James M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212946/
https://ncbi.nlm.nih.gov/pubmed/16172256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050811
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