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The structure of human CD23 and its interactions with IgE and CD21
The low-affinity immunoglobulin E (IgE) receptor, CD23 (FcɛRII), binds both IgE and CD21 and, through these interactions, regulates the synthesis of IgE, the antibody isotype that mediates the allergic response. We have determined the three-dimensional structure of the C-type lectin domain of CD23 i...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212946/ https://ncbi.nlm.nih.gov/pubmed/16172256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050811 |
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