Repression of SPI2 transcription by nitric oxide-producing, IFNγ-activated macrophages promotes maturation of Salmonella phagosomes

By remodeling the phagosomal membrane, the type III secretion system encoded within the Salmonella pathogenicity island-2 (SPI2) helps Salmonella thrive within professional phagocytes. We report here that nitric oxide (NO) generated by IFNγ-activated macrophages abrogates the intracellular survival...

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Main Authors: McCollister, Bruce D., Bourret, Travis J., Gill, Ronald, Jones-Carson, Jessica, Vázquez-Torres, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212872/
https://ncbi.nlm.nih.gov/pubmed/16129704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050246
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