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Salmonella SPI1 Effector SipA Persists after Entry and Cooperates with a SPI2 Effector to Regulate Phagosome Maturation and Intracellular Replication

Salmonellae employ two type III secretion systems (T3SSs), SPI1 and SPI2, to deliver virulence effectors into mammalian cells. SPI1 effectors, including actin-binding SipA, trigger initial bacterial uptake, whereas SPI2 effectors promote subsequent replication within customized Salmonella-containing...

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Detalhes bibliográficos
Main Authors: Brawn, Lyndsey C., Hayward, Richard D., Koronakis, Vassilis
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885946/
https://ncbi.nlm.nih.gov/pubmed/18005682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2007.02.001
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