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N(2)O(3) enhances the nitrosative potential of IFNγ-primed macrophages in response to Salmonella

We show here that the nitric oxide (NO)-detoxifying Hmp flavohemoprotein increases by 3-fold the transcription of the Salmonella pathogenicity island 2 (SPI2) in macrophages expressing a functional inducible NO synthase (iNOS). However, Hmp does not prevent NO-related repression of SPI2 transcriptio...

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Detalhes bibliográficos
Main Authors: McCollister, Bruce D., Myers, Jesse T., Jones-Carson, Jessica, Husain, Maroof, Bourret, Travis J., Vázquez-Torres, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329578/
https://ncbi.nlm.nih.gov/pubmed/18086377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2007.09.019
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