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T cells that cannot respond to TGF-β escape control by CD4(+)CD25(+) regulatory T cells

CD4(+)CD25(+) regulatory T (T reg) cells play a pivotal role in control of the immune response. Transforming growth factor-β (TGF-β) has been shown to be required for T reg cell activity; however, precisely how it is involved in the mechanism of suppression is poorly understood. Using the T cell tra...

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Bibliografiska uppgifter
Huvudupphovsmän: Fahlén, Linda, Read, Simon, Gorelik, Leonid, Hurst, Stephen D., Coffman, Robert L., Flavell, Richard A., Powrie, Fiona
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212836/
https://ncbi.nlm.nih.gov/pubmed/15753207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040685
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