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Lnk Inhibits Tpo–mpl Signaling and Tpo-mediated Megakaryocytopoiesis
Thrombopoietin (Tpo) is the primary cytokine regulating megakaryocyte development and platelet production. Tpo signaling through its receptor, c-mpl, activates multiple pathways including signal transducer and activator of transcription (STAT)3, STAT5, phosphoinositide 3-kinase–Akt, and p42/44 mitog...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212736/ https://ncbi.nlm.nih.gov/pubmed/15337790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040762 |
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