Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice

Congenital amegakaryocytic thrombocytopenia (CAMT) is a disorder caused by c-MPL mutations that impair thrombopoietin (TPO) signalling, resulting in a near-absence of megakaryocytes (MKs). While this phenotype is consistent in adults, neonates with CAMT can present with severe thrombocytopenia despi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Thromb Haemost
Main Authors: Lorenz, Viola, Ramsey, Haley, Liu, Zhi-Jian, Italiano, Joseph, Hoffmeister, Karin, Bihorel, Sihem, Mager, Donald, Hu, Zhongbo, Slayton, William B., Kile, Benjamin T., Sola-Visner, Martha, Ferrer-Marin, Francisca
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911346/
https://ncbi.nlm.nih.gov/pubmed/29212120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH17-06-0433
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados