Immunoprevention of Basal Cell Carcinomas with Recombinant Hedgehog-interacting Protein

Basal cell carcinomas (BCCs) are driven by abnormal hedgehog signaling and highly overexpress several hedgehog target genes. We report here our use of one of these target genes, hedgehog-interacting protein (Hip1), as a tumor-associated antigen for immunoprevention of BCCs in Ptch1(+/−) mice treated...

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Detaylı Bibliyografya
Asıl Yazarlar: Vogt, Annika, Chuang, Pao-Tien, Hebert, Jennifer, Hwang, Jimmy, Lu, Ying, Kopelovich, Levy, Athar, Mohammad, Bickers, David R., Epstein, Ervin H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2004
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212732/
https://ncbi.nlm.nih.gov/pubmed/15024045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031190
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