Immunoprevention of Basal Cell Carcinomas with Recombinant Hedgehog-interacting Protein

Basal cell carcinomas (BCCs) are driven by abnormal hedgehog signaling and highly overexpress several hedgehog target genes. We report here our use of one of these target genes, hedgehog-interacting protein (Hip1), as a tumor-associated antigen for immunoprevention of BCCs in Ptch1(+/−) mice treated...

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Bibliografiske detaljer
Main Authors: Vogt, Annika, Chuang, Pao-Tien, Hebert, Jennifer, Hwang, Jimmy, Lu, Ying, Kopelovich, Levy, Athar, Mohammad, Bickers, David R., Epstein, Ervin H.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212732/
https://ncbi.nlm.nih.gov/pubmed/15024045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031190
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