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Stimulus-dependent Synergism of the Antiapoptotic Tumor Necrosis Factor Receptor–associated Factor 2 (TRAF2) and Nuclear Factor κB Pathways

Tumor necrosis factor (TNF) signaling leads to pleiotropic responses in a wide range of cell types, in part by activating antiapoptotic and proapoptotic signaling pathways. Thus, although TNF can cause apoptosis and may prove useful in the treatment of malignancies, most cells are resistant to TNF-i...

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Autori principali: Lee, Soo Young, Kaufman, David R., Mora, Ana L., Santana, Angela, Boothby, Mark, Choi, Yongwon
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212489/
https://ncbi.nlm.nih.gov/pubmed/9763618
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