The Human Toll Signaling Pathway: Divergence of Nuclear Factor κB and JNK/SAPK Activation Upstream of Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6)

The human homologue of Drosophila Toll (hToll) is a recently cloned receptor of the interleukin 1 receptor (IL-1R) superfamily, and has been implicated in the activation of adaptive immunity. Signaling by hToll is shown to occur through sequential recruitment of the adapter molecule MyD88 and the IL...

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Bibliographische Detailangaben
Hauptverfasser: Muzio, Marta, Natoli, Gioacchino, Saccani, Simona, Levrero, Massimo, Mantovani, Alberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1998
Schlagworte:
Brief Definitive Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212359/
https://ncbi.nlm.nih.gov/pubmed/9625770
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