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Processing of Switch Transcripts Is Required for Targeting of Antibody Class Switch Recombination

Antibody class switching is mediated by somatic recombination between switch regions of the immunoglobulin heavy chain gene locus. Targeting of recombination to particular switch regions is strictly regulated by cytokines through the induction of switch transcripts starting 5′ of the repetitive swit...

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Dettagli Bibliografici
Autori principali: Hein, Katharina, Lorenz, Matthias G.O., Siebenkotten, Gregor, Petry, Katja, Christine, Rainer, Radbruch, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212419/
https://ncbi.nlm.nih.gov/pubmed/9858523
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