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Processing of Switch Transcripts Is Required for Targeting of Antibody Class Switch Recombination

Antibody class switching is mediated by somatic recombination between switch regions of the immunoglobulin heavy chain gene locus. Targeting of recombination to particular switch regions is strictly regulated by cytokines through the induction of switch transcripts starting 5′ of the repetitive swit...

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Detalhes bibliográficos
Main Authors: Hein, Katharina, Lorenz, Matthias G.O., Siebenkotten, Gregor, Petry, Katja, Christine, Rainer, Radbruch, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212419/
https://ncbi.nlm.nih.gov/pubmed/9858523
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