Chemical Interplay in the Mechanism of Partial Agonist Activation in α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid Receptors

α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, one subtype in the family of ionotropic glutamate receptors, are the main receptors responsible for excitatory signaling in the mammalian central nervous system. Previous studies utilitizing the isolated ligand binding domain of...

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Hlavní autoři: Mankiewicz, Kimberly A., Rambhadran, Anu, Wathen, Lisa, Jayaraman, Vasanthi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212281/
https://ncbi.nlm.nih.gov/pubmed/18081322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702004b
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