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Chemical Interplay in the Mechanism of Partial Agonist Activation in α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid Receptors

α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, one subtype in the family of ionotropic glutamate receptors, are the main receptors responsible for excitatory signaling in the mammalian central nervous system. Previous studies utilitizing the isolated ligand binding domain of...

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Detalhes bibliográficos
Main Authors: Mankiewicz, Kimberly A., Rambhadran, Anu, Wathen, Lisa, Jayaraman, Vasanthi
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212281/
https://ncbi.nlm.nih.gov/pubmed/18081322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702004b
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