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Chemical Interplay in the Mechanism of Partial Agonist Activation in α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid Receptors

α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, one subtype in the family of ionotropic glutamate receptors, are the main receptors responsible for excitatory signaling in the mammalian central nervous system. Previous studies utilitizing the isolated ligand binding domain of...

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Autors principals: Mankiewicz, Kimberly A., Rambhadran, Anu, Wathen, Lisa, Jayaraman, Vasanthi
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212281/
https://ncbi.nlm.nih.gov/pubmed/18081322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702004b
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