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Yeast as a model of human mitochondrial tRNA base substitutions: Investigation of the molecular basis of respiratory defects
We investigate the relationships between acylation defects and structure alterations due to base substitutions in yeast mitochondrial (mt) tRNA(UUR) (Leu). The studied substitutions are equivalent to the A3243G and T3250C human pathogenetic tRNA mutations. Our data show that both mutations can produ...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212258/ https://ncbi.nlm.nih.gov/pubmed/18065717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.740108 |
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