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Peptides from aminoacyl-tRNA synthetases can cure the defects due to mutations in mt tRNA genes

Recent results from several laboratories have confirmed that human and yeast leucyl- and valyl-tRNA synthetases can rescue the respiratory defects due to mutations in mitochondrial tRNA genes. In this report we show that this effect cannot be ascribed to the catalytic activity per se and that isolat...

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Detalhes bibliográficos
Main Authors: Francisci, Silvia, Montanari, Arianna, De Luca, Cristina, Frontali, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210327/
https://ncbi.nlm.nih.gov/pubmed/21903180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2011.08.006
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