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The bacterial toxin RelE induces specific mRNA cleavage in the A site of the eukaryote ribosome
RelE/RelB is a well-characterized toxin–anti-toxin pair involved in nutritional stress responses in Bacteria and Archae. RelE lacks any eukaryote homolog, but we demonstrate here that it efficiently and specifically cleaves mRNA in the A site of the eukaryote ribosome. The cleavage mechanism is simi...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212246/ https://ncbi.nlm.nih.gov/pubmed/18083838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.693208 |
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