The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE

Translational control is widely used to adjust gene expression levels. During the stringent response in bacteria, mRNA is degraded on the ribosome by the ribosome-dependent endonuclease, RelE. The molecular basis for recognition of the ribosome and mRNA by RelE and the mechanism of cleavage are unkn...

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Main Authors: Neubauer, Cajetan, Gao, Yong-Gui, Andersen, Kasper R., Dunham, Christine M., Kelley, Ann C., Hentschel, Jendrik, Gerdes, Kenn, Ramakrishnan, V., Brodersen, Ditlev E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807027/
https://ncbi.nlm.nih.gov/pubmed/20005802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.11.015
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