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A Natural Immunological Adjuvant Enhances T Cell Clonal Expansion through a CD28-dependent, Interleukin (IL)-2–independent Mechanism

The adoptive transfer of naive CD4(+) T cell receptor (TCR) transgenic T cells was used to investigate the mechanisms by which the adjuvant lipopolysaccharide (LPS) enhance T cell clonal expansion in vivo. Subcutaneous administration of soluble antigen (Ag) resulted in rapid and transient accumulati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Khoruts, Alexander, Mondino, Anna, Pape, Kathryn A., Reiner, Steven L., Jenkins, Marc K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212094/
https://ncbi.nlm.nih.gov/pubmed/9432980
Tagiau: Ychwanegu Tag
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