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Enhanced TCR-induced Apoptosis in Interferon Regulatory Factor 4–deficient CD4(+) Th Cells
Transcription factors of the interferon regulatory factor (IRF) family contribute to the regulation of cell proliferation and apoptosis. Here, we show that CD4(+) T helper (Th) cells lacking IRF4 (IRF4(−/−)) are highly sensitive to apoptosis. After infection of IRF4(−/−) mice with the protozoan para...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212018/ https://ncbi.nlm.nih.gov/pubmed/15249594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040182 |
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