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Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4

Certain IFN regulatory factor (IRF) transcription factors indirectly influence T helper (Th) cell differentiation by regulating the production of IL-12. Here, we show that IRF4 directly regulates Th cell differentiation in vitro and in vivo during murine leishmaniasis. In the absence of IRF4, IL-12-...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Lohoff, Michael, Mittrücker, Hans-Willi, Prechtl, Stefan, Bischof, Susi, Sommer, Frank, Kock, Sonja, Ferrick, David A., Duncan, Gordon S., Gessner, Andre, Mak, Tak W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129350/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12189207/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.182425099
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