GITR Activation Induces an Opposite Effect on Alloreactive CD4(+) and CD8(+) T Cells in Graft-Versus-Host Disease

Glucocorticoid-induced tumor necrosis factor receptor family-related gene (GITR) is a member of the tumor necrosis factor receptor (TNFR) family that is expressed at low levels on unstimulated T cells, B cells, and macrophages. Upon activation, CD4(+) and CD8(+) T cells up-regulate GITR expression,...

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Detalhes bibliográficos
Main Authors: Muriglan, Stephanie J., Ramirez-Montagut, Teresa, Alpdogan, Onder, van Huystee, Thomas W., Eng, Jeffrey M., Hubbard, Vanessa M., Kochman, Adam A., Tjoe, Kartono H., Riccardi, Carlo, Pandolfi, Pier Paolo, Sakaguchi, Shimon, Houghton, Alan N., van den Brink, Marcel R.M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212013/
https://ncbi.nlm.nih.gov/pubmed/15249593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040116
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