Absence of inducible costimulator on alloreactive T cells reduces graft versus host disease and induces Th2 deviation

Inducible costimulator (ICOS) is expressed on activated and memory T cells and is involved in the regulation of cytokine production. We studied the role of ICOS on alloreactive T cells in graft versus host disease (GVHD) and determined that ICOS expression was up-regulated on alloreactive T cells in...

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Detalhes bibliográficos
Main Authors: Hubbard, Vanessa M., Eng, Jeffrey M., Ramirez-Montagut, Teresa, Tjoe, Kartono H., Muriglan, Stephanie J., Kochman, Adam A., Terwey, Theis H., Willis, Lucy M., Schiro, Rafaella, Heller, Glen, Murphy, George F., Liu, Chen, Alpdogan, Onder, van den Brink, Marcel R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895338/
https://ncbi.nlm.nih.gov/pubmed/15956289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0410
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