Absence of inducible costimulator on alloreactive T cells reduces graft versus host disease and induces Th2 deviation

Inducible costimulator (ICOS) is expressed on activated and memory T cells and is involved in the regulation of cytokine production. We studied the role of ICOS on alloreactive T cells in graft versus host disease (GVHD) and determined that ICOS expression was up-regulated on alloreactive T cells in...

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Autors principals: Hubbard, Vanessa M., Eng, Jeffrey M., Ramirez-Montagut, Teresa, Tjoe, Kartono H., Muriglan, Stephanie J., Kochman, Adam A., Terwey, Theis H., Willis, Lucy M., Schiro, Rafaella, Heller, Glen, Murphy, George F., Liu, Chen, Alpdogan, Onder, van den Brink, Marcel R. M.
Format: Artigo
Idioma:Inglês
Publicat: © 2005 by The American Society of Hematology 2005
Matèries:
Transplantation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895338/
https://ncbi.nlm.nih.gov/pubmed/15956289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0410
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