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Age-related Defects in CD4 T Cell Cognate Helper Function Lead to Reductions in Humoral Responses

With increasing age, the ability to produce protective antibodies in response to immunization declines, leading to a reduced efficacy of vaccination in the elderly. To examine the effect of age on the cognate function of CD4 T cells, we have used a novel adoptive transfer model that allows us to com...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Eaton, Sheri M., Burns, Eve M., Kusser, Kimberly, Randall, Troy D., Haynes, Laura
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211991/
https://ncbi.nlm.nih.gov/pubmed/15611289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041395
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