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Proinflammatory Adjuvants Enhance the Cognate Helper Activity of Aged CD4 T Cells
Age-related declines in humoral responses contribute to the reduced efficacy of vaccines in older populations. Using an adoptive transfer model, we have shown that age-related intrinsic declines in CD4 T cell function contribute significantly to the reduced humoral responses observed with aging, res...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023905/ https://ncbi.nlm.nih.gov/pubmed/19414765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804226 |
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