Loss of Bim Increases T Cell Production and Function in Interleukin 7 Receptor–deficient Mice

Interleukin (IL)-7 receptor (R) signaling is essential for T and B lymphopoiesis by promoting proliferation, differentiation, and survival of cells. Mice lacking either IL-7 or the IL-7Rα chain have abnormally low numbers of immature as well as mature T and B lymphocytes. Transgenic expression of th...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Pellegrini, Marc, Bouillet, Philippe, Robati, Mikara, Belz, Gabrielle T., Davey, Gayle M., Strasser, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2004
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211860/
https://ncbi.nlm.nih.gov/pubmed/15504823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041328
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky