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Loss of Bim Increases T Cell Production and Function in Interleukin 7 Receptor–deficient Mice
Interleukin (IL)-7 receptor (R) signaling is essential for T and B lymphopoiesis by promoting proliferation, differentiation, and survival of cells. Mice lacking either IL-7 or the IL-7Rα chain have abnormally low numbers of immature as well as mature T and B lymphocytes. Transgenic expression of th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211860/ https://ncbi.nlm.nih.gov/pubmed/15504823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041328 |
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