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ATM Is Required for Efficient Recombination between Immunoglobulin Switch Regions
Ataxia telangiectasia mutated (ATM) kinase is critical for initiating the signaling pathways that lead to cell cycle checkpoints and DNA double strand break repair. In the absence of ATM, humans and mice show a primary immunodeficiency that includes low serum antibody titers, but the role of ATM in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211855/ https://ncbi.nlm.nih.gov/pubmed/15520243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041162 |
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