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The Alzheimer's disease β-secretase enzyme, BACE1

The pathogenesis of Alzheimer's disease is highly complex. While several pathologies characterize this disease, amyloid plaques, composed of the β-amyloid peptide are hallmark neuropathological lesions in Alzheimer's disease brain. Indeed, a wealth of evidence suggests that β-amyloid is ce...

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Detalhes bibliográficos
Main Authors: Cole, Sarah L, Vassar, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211305/
https://ncbi.nlm.nih.gov/pubmed/18005427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-2-22
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