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Conformational variants of class II MHC/peptide complexes induced by N- and C-terminal extensions of minimal peptide epitopes

Class II MHC molecules are known to exist in conformational variants. “Floppy” and “compact” forms of murine MHC molecules, for example, are discriminated by their migration behavior on SDS/PAGE and represent empty and ligand-loaded forms. Here we show that formation of distinctly faster-migrating l...

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Detalhes bibliográficos
Main Authors: Rötzschke, O., Falk, K., Mack, J., Lau, J. M., Jung, G., Strominger, J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22105/
https://ncbi.nlm.nih.gov/pubmed/10377434
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