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Inhibition of NF-κB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO
The link between the NF-κB signal transduction pathway and cancer is now well established. Inhibiting this pathway is therefore a promising approach in the treatment of certain cancers through a pro-apoptotic effect in malignant cells. Owing to its central role in the pathway, the IκB kinase (IKK) c...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Wiley-Blackwell
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206981/ https://ncbi.nlm.nih.gov/pubmed/17766391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072924907 |
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