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Crystallographic studies of the complexes of antiviral protein griffithsin with glucose and N-acetylglucosamine

Crystal structures of complexes of an antiviral lectin griffithsin (GRFT) with glucose and N-acetylglucosamine were solved and refined at high resolution. In both complexes, all six monosaccharide-binding sites of GRFT were occupied and the mode of binding was similar to that of mannose. In our prev...

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Autores principales: Ziółkowska, Natasza E., Shenoy, Shilpa R., O'Keefe, Barry R., Wlodawer, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206701/
https://ncbi.nlm.nih.gov/pubmed/17567736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072889407
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