Decreased Nociceptive Sensitization in Mice Lacking the Fragile X Mental Retardation Protein: Role of mGluR1/5 and mTOR

Fragile X mental retardation is caused by silencing of the gene (FMR1) that encodes the RNA-binding protein (FMRP) that influences translation in neurons. A prominent feature of the human disorder is self-injurious behavior, suggesting an abnormality in pain processing. Moreover, FMRP regulates grou...

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Auteurs principaux: Price, Theodore J., Rashid, Md Harunor, Millecamps, Magali, Sanoja, Raul, Entrena, Jose M., Cervero, Fernando
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206543/
https://ncbi.nlm.nih.gov/pubmed/18094233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4383-07.2007
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