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mTOR Activation Is Required for the Antidepressant Effects of mGluR(2/3) Blockade
Recent studies demonstrate that ketamine, a fast-acting antidepressant, rapidly activates the mammalian target of rapamycin (mTOR) and increases synaptogenesis in the prefrontal cortex (PFC). Because of the side effect and abuse potential of ketamine we are investigating alternative agents that prod...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580765/ https://ncbi.nlm.nih.gov/pubmed/22114864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145711001702 |
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