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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

The rapid antidepressant response after ketamine administration in treatment resistant depressed patients suggests a possible new approach for treating mood disorders compared to the weeks or months required for standard medications. However, the mechanisms underlying this action of ketamine have no...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Nanxin, Lee, Boyoung, Liu, Rong-Jian, Banasr, Mounira, Dwyer, Jason M., Iwata, Masaaki, Li, Xiao-Yuan, Aghajanian, George, Duman, Ronald S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116441/
https://ncbi.nlm.nih.gov/pubmed/20724638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1190287
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