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In vitro binding of single-stranded RNA by human Dicer
While Dicer alone has been shown to form stable complexes with double-stranded RNAs and short interfering RNAs, its interactions with single-stranded RNAs (ssRNAs) have not been characterized. Here, we show that recombinant human Dicer alone can bind 21-nt ssRNAs in vitro, independent of their seque...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206536/ https://ncbi.nlm.nih.gov/pubmed/18023283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.11.010 |
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