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Ribonuclease activity and RNA binding of recombinant human Dicer

RNA silencing phenomena, known as post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference (RNAi) in animals, are mediated by double-stranded RNA (dsRNA) and mechanistically intersect at the ribonuclease Dicer. Here, we report cloning and expression of the 218 kDa human...

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Detalhes bibliográficos
Main Authors: Provost, Patrick, Dishart, David, Doucet, Johanne, Frendewey, David, Samuelsson, Bengt, Rådmark, Olof
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC131075/
https://ncbi.nlm.nih.gov/pubmed/12411504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf578
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