Ribonuclease activity and RNA binding of recombinant human Dicer

RNA silencing phenomena, known as post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference (RNAi) in animals, are mediated by double-stranded RNA (dsRNA) and mechanistically intersect at the ribonuclease Dicer. Here, we report cloning and expression of the 218 kDa human...

Полное описание

Библиографические подробности

Опубликовано в::	EMBO J
Главные авторы:	Provost, Patrick, Dishart, David, Doucet, Johanne, Frendewey, David, Samuelsson, Bengt, Rådmark, Olof
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Publishing Group 2002
Предметы:	Articles
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC131075/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12411504/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf578
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