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Two distinct mechanisms of silencing by the KvDMR1 imprinting control region
Imprinting control regions (ICRs) are known to repress genes by utilizing one of two mechanisms, CTCF-mediated insulation or the transcription of non-coding RNAs (ncRNAs). The KvDMR1 ICR contains both the promoter for the Kcnq1ot1 ncRNA and two CTCF-binding sites located within sequences exhibiting...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206141/ https://ncbi.nlm.nih.gov/pubmed/18079696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601960 |
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