Allele-Specific Binding of CTCF to the Multipartite Imprinting Control Region KvDMR1

Paternal deletion of the imprinting control region (ICR) KvDMR1 results in loss of expression of the Kcnq1ot1 noncoding RNA and derepression of flanking paternally silenced genes. Truncation of Kcnq1ot1 also results in the loss of imprinted expression of these genes in most cases, demonstrating a ro...

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Hlavní autoři: Fitzpatrick, Galina V., Pugacheva, Elena M., Shin, Jong-Yeon, Abdullaev, Ziedulla, Yang, Youwen, Khatod, Kavita, Lobanenkov, Victor V., Higgins, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899897/
https://ncbi.nlm.nih.gov/pubmed/17242189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02036-06
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