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Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

We report here the cloning, expression, and characterization of a dual-substrate, cAMP and cGMP, cyclic nucleotide phosphodiesterase (PDE) from mouse. This PDE contains the consensus sequence for a PDE catalytic domain, but shares <50% sequence identity with the catalytic domains of all other kno...

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Detalhes bibliográficos
Main Authors: Soderling, Scott H., Bayuga, Sharon J., Beavo, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22059/
https://ncbi.nlm.nih.gov/pubmed/10359840
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