Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

We report here the cloning, expression, and characterization of a dual-substrate, cAMP and cGMP, cyclic nucleotide phosphodiesterase (PDE) from mouse. This PDE contains the consensus sequence for a PDE catalytic domain, but shares <50% sequence identity with the catalytic domains of all other known...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Soderling, Scott H., Bayuga, Sharon J., Beavo, Joseph A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1999
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22059/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359840/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.12.7071
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