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Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

We report here the cloning, expression, and characterization of a dual-substrate, cAMP and cGMP, cyclic nucleotide phosphodiesterase (PDE) from mouse. This PDE contains the consensus sequence for a PDE catalytic domain, but shares <50% sequence identity with the catalytic domains of all other known...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Soderling, Scott H., Bayuga, Sharon J., Beavo, Joseph A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359840/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.12.7071
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