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Guanosine triphosphatase stimulation of oncogenic Ras mutants

Interest in the guanosine triphosphatase (GTPase) reaction of Ras as a molecular drug target stems from the observation that, in a large number of human tumors, Ras is characteristically mutated at codons 12 or 61, more rarely 13. Impaired GTPase activity, even in the presence of GTPase activating p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ahmadian, Mohammad Reza, Zor, Tsaffrir, Vogt, Dorothee, Kabsch, Wolfgang, Selinger, Zvi, Wittinghofer, Alfred, Scheffzek, Klaus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC22057/
https://ncbi.nlm.nih.gov/pubmed/10359839
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