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Mutations that mimic phosphorylation of the HIV-1 matrix protein do not perturb the myristyl switch
Recent studies indicate that the matrix domain (MA) of the HIV-1 Gag polyprotein directs Gag to the plasma membrane for virus assembly via a phosphatidylinositol-4,5-bisphosphate (PIP(2))–dependent myristyl switch mechanism. MA also has been reported to direct nuclear trafficking via nuclear import...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2203364/ https://ncbi.nlm.nih.gov/pubmed/17656588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072987607 |
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