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Point mutations in the HIV-1 matrix protein turn off the myristyl switch
During the late phase of HIV-1 replication, newly synthesized retroviral Gag proteins are targeted to lipid raft regions of specific cellular membranes, where they assemble and bud to form new virus particles. Gag binds preferentially to the plasma membrane (PM) of most hematopoietic cell types, a p...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1853300/ https://ncbi.nlm.nih.gov/pubmed/17188710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.068 |
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