Point mutations in the HIV-1 matrix protein turn off the myristyl switch

During the late phase of HIV-1 replication, newly synthesized retroviral Gag proteins are targeted to lipid raft regions of specific cellular membranes, where they assemble and bud to form new virus particles. Gag binds preferentially to the plasma membrane (PM) of most hematopoietic cell types, a p...

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Bibliografiske detaljer
Main Authors: Saad, Jamil S., Loeliger, Erin, Luncsford, Paz, Liriano, Mellisa, Tai, Janet, Kim, Andrew, Miller, Jaime, Joshi, Anjali, Freed, Eric O., Summers, Michael F.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853300/
https://ncbi.nlm.nih.gov/pubmed/17188710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.068
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